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讲师
尹昊琰
发布时间:2022-01-26    阅读次数:8704

姓 名:
尹昊琰
职 称:
讲师
职 务:
 
所属系:
化学系
邮 箱:

yinhaoyan@hfut.edu.cn

电 话:


个人简历

2011年9月–2015年7月,北京大学 化学与分子工程学院 化学专业学习,获学士学位;

2015年9月–2021年6月,北京大学 化学与分子工程学院无机化学专业学习,硕博连读,获博士学位;

2021年12月–至今,合肥工业大学 化学与化工学院,讲师

主要研究领域、方向

基于金属配合物的新型小分子荧光探针和金属药物的设计合成、性质及机制研究以及探索它们在生物医学领域的应用和临床转化

研究成果(代表性成果)

围绕新型小分子金属配合物荧光探针和金属药物进行研究,近年来已在包括Angew. Chem. Int. Ed., Chem. Sci., Chem. Commun., Eur. J. Inorg. Chem.在内的国际重要学术期刊上发表SCI学术论文十余篇。

目前承担科研项目 


获奖及专利情况  

获批专利:

1. Junlong Zhang, Haoyan Yin, Bingwu Wang, Main-group metal complex with cancer cell killing ability and preparation and application thereof, 2019, Patent WO 2019214691

著作论文(代表作)

1. Hao-Yan Yin+, Jiu-Jiao Gao+, Xuemin Chen+, Bin Ma+, Zi-Shu Yang, Juan Tang, Bing-Wu Wang, Tianfeng Chen, Chu Wang, Song Gao, Jun-Long Zhang*, A Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as an Anticancer Target, Angew. Chem. Int. Ed., 2020, 59, 20147-20153 (+: These authors contributed equally to this work).

2. Hao-Yan Yin, Jing Lai, Juan Tang, Yanli Shang*, and Jun-Long Zhang*, A cryptand-type aluminum tris(salophen) complex: synthesis, characterization, and cell imaging application, Inorganics, 2018, 6, 20;

3. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Sulfur speciation defined subcellular localization of coumarin derivatives: Correlation of structural relationship to biological behaviors, Chin. Chem. Lett., 2018, 29, 267-270.

4. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Luminescent metal salen complex as intracellular microviscosity fluorescent sensor, Sci. Sin. Chim., 2017, 47, 267.

5. Hao-Yan Yin, Juan Tang, Jun-Long Zhang*, Introducing Metallosalens to Biological Studies: The Renaissance of Traditional Coordination Complexes, Eur. J. Inorg. Chem., 2017, 44, 5085-5093.

6. Juan Tang, Hao-Yan Yin and Jun-Long Zhang*, A luminescent aluminium salen complex allows for monitoring dynamic vesicle trafficking from the Golgi apparatus to lysosomes in living cells, Chem. Sci., 2018, 9, 1931-1939.

7. Juan Tang, Hao-Yan Yin and Jun-Long Zhang*, Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells, Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells, Elsevier press, 2017.

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